MolNFT v1 · #168355 · protein

The external aldimine form of the salmonella thypi wild-type tryptophan synthase in open conformation showing multiple side chain conformations for the residue beta Q114 and sodium ion at the metal coordination site. one of the beta-Q114 rotamer conformations allows a hydrogen bond to form with the plp oxygen at the position 3 in the ring.

6WDU: “The external aldimine form of the salmonella thypi wild-type tryptophan synthase in open conformation showing…”. X-ray diffraction, 1 ligand (NA). MolNFT v1 #168355 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6WDU
Type: protein
Length: 651 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P00929, P0A2K1
Ligands: NA

Structure

x-ray diffraction · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	254	—	P00929
B	—	protein	397	—	P0A2K1

Ligands and binding sites

NA · Sodium ion · metal · 2 copies · chains B
DMS · Dimethyl sulfoxide · additive · 14 copies · chains A, B
EDO · 1,2-ethanediol · additive · 8 copies · chains A, B
PEG · Di(hydroxyethyl)ether · additive · 2 copies · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6WDU · The external aldimine form of the Salmonella thypi wild-type tryptophan synthase in open… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P00929
Every structure of UniProt P0A2K1
Elsewhere: RCSB PDB 6WDU · PDBe 6WDU · UniProt P00929 · UniProt P0A2K1

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.