TTLL6 bound to gamma-elongation analog

Structure

x-ray diffraction · 5 distinct chains.

Ligands and binding sites

• S3A · (2~{S})-2-[[[(3~{R})-3-acetamido-4-oxidanyl-4-oxidanylidene-butyl]-phosphonooxy-phosphoryl]methyl]pentanedioic acid · ligand · 4 copies · chains A, C, B, D
• ADP · Adenosine-5'-diphosphate · ligand · 4 copies · chains A, B, C, D
• S37 · (2~{S})-2-[[[(3~{S})-3-acetamido-4-oxidanyl-4-oxidanylidene-butyl]-oxidanyl-phosphoryl]methyl]pentanedioic acid · ligand · 2 copies · chains A, D
• MG · Magnesium ion · metal · 8 copies · chains A, B, C, D
• GOL · Glycerol · additive · 32 copies · chains A, C, B, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 6VZV · TTLL6 bound to gamma-elongation analog · the same entry in another collection · chain J against J, TM-score 1.00
• A4Q9E8 · AlphaFold monomer V2.0 prediction for tubulin polyglutamylase TTLL6 (A4Q9E8) · a predicted model of the same protein · chain D against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt A4Q9E8
• Elsewhere: RCSB PDB 6VZV · PDBe 6VZV · UniProt A4Q9E8