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MolNFT v1 · #167804 · protein + DNA

Crystal structure of a mycobacterium smegmatis transcription initiation complex with rifampicin-resistant RNA polymerase

6VVV: “Crystal structure of a mycobacterium smegmatis transcription initiation complex with rifampicin-resistant RNA…”. X-ray diffraction, 2 ligands (ZN, SO4). MolNFT v1 #167804 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6VVV
Type
protein + DNA
Length
2,999 residues
Chains
10
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
A0QZ11, A0QSL8, P60281, A0QS66, A0QWT1, A0QW02
Ligands
ZN, SO4

Structure

x-ray diffraction · 10 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
J—protein88—A0QZ11
A—protein223—A0QSL8
B—protein235—A0QSL8
C—protein790—P60281
D—protein1174—A0QS66
E—protein77—A0QWT1
F—protein302—A0QW02
O—dna31——
T—protein53—A0QSL8
P—dna26——

Ligands and binding sites

  • ZN · Zinc ion · metal · 2 copies · chains D
  • SO4 · Sulfate ion · ion · 12 copies · chains D, F, O, P

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6VVV · Crystal structure of a Mycobacterium smegmatis transcription initiation complex with… · the same entry in another collection · chain P against P, TM-score 1.00
  • P60281 · AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit beta (P60281) · a predicted model of the same protein · chain C against A, TM-score 0.98
  • A0QS66 · AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit beta' (A0QS66) · a predicted model of the same protein · chain D against A, TM-score 0.97

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