MolNFT v1 · #167456 · protein

Crystal structure of human alpha 1,6-fucosyltransferase, FUT8 bound to GDP and A2SGP

6VLD: “Crystal structure of human alpha 1,6-fucosyltransferase, FUT8 bound to GDP and A2SGP”. X-ray diffraction, 5 ligands (GDP, NAG, MAN). MolNFT v1 #167456 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6VLD
Type: protein
Length: 1,858 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q9BYC5
Ligands: GDP, NAG, MAN, BMA, SO4

Structure

x-ray diffraction · 4 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	468	—	Q9BYC5
B	—	protein	470	—	Q9BYC5
G	—	protein	466	—	Q9BYC5
H	—	protein	454	—	Q9BYC5

Ligands and binding sites

GDP · Guanosine-5'-diphosphate · ligand · 2 copies · chains A, B
NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 16 copies · chains A, B, G, H
MAN · alpha-D-mannopyranose · sugar · 8 copies · chains A, B, G, H
BMA · beta-D-mannopyranose · sugar · 4 copies · chains A, B, G, H
SO4 · Sulfate ion · ion · 12 copies · chains A, B, G, H

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6VLD · Crystal structure of human alpha 1,6-fucosyltransferase, FUT8 bound to GDP and A2SGP · the same entry in another collection · chain B against B, TM-score 1.00
Q9BYC5 · AlphaFold monomer V2.0 prediction for alpha-(1,6)-fucosyltransferase (Q9BYC5) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9BYC5
Elsewhere: RCSB PDB 6VLD · PDBe 6VLD · UniProt Q9BYC5

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