MolNFT v1 · #167172 · protein
Crystal structure of E.COLI rpph in complex with CTP
6VCR · RNA pyrophosphohydrolase: “Crystal structure of E.COLI rpph in complex with CTP”. X-ray diffraction, 3 ligands (CTP, PPV, SO4), 1 pocket (best druggability 0.40). MolNFT v1 #167172 on GenesisL1: 3D structure, binding sites and…
- PDB
- 6VCR
- Type
- protein
- Length
- 161 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RNA pyrophosphohydrolase
- EC
- 3.6.1.-
- UniProt
- P0A776
- Ligands
- CTP, PPV, SO4
- Pockets
- 1 · best druggability 0.40
Structure
x-ray diffraction · 1 distinct chain · 30% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RNA pyrophosphohydrolase (EC 3.6.1.-) | protein | 161 | 30% helix, 30% strand | P0A776 |
Ligands and binding sites
- CTP · Cytidine-5'-triphosphate · ligand · 3 copies · chains A
- PPV · Pyrophosphate · ligand · chains A
- SO4 · Sulfate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 165 | 0.40 | 0.73 | 30 | CTP |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A776
- Elsewhere: RCSB PDB 6VCR · PDBe 6VCR · UniProt P0A776
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