MolNFT v1 · #165438 · protein

Unliganded human CD73 (5'-nucleotidase) in the open state

6TVE: “Unliganded human CD73 (5'-nucleotidase) in the open state”. X-ray diffraction, 2 ligands (ZN, CA). MolNFT v1 #165438 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6TVE
Type: protein
Length: 524 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P21589
Ligands: ZN, CA

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
P	—	protein	524	—	P21589

Ligands and binding sites

ZN · Zinc ion · metal · 2 copies · chains P
CA · Calcium ion · metal · chains P
DMS · Dimethyl sulfoxide · additive · 8 copies · chains P
GOL · Glycerol · additive · 3 copies · chains P

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6TVE · Unliganded human CD73 (5'-nucleotidase) in the open state · the same entry in another collection · chain P against P, TM-score 1.00
P21589 · AlphaFold monomer V2.0 prediction for 5'-nucleotidase (P21589) · a predicted model of the same protein · chain P against A, TM-score 0.69

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P21589
Elsewhere: RCSB PDB 6TVE · PDBe 6TVE · UniProt P21589

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