MolNFT v1 · #165133 · protein
Crystal structure of the DHR2 domain of DOCK10 in complex with CDC42
6TKZ: “Crystal structure of the DHR2 domain of DOCK10 in complex with CDC42”. X-ray diffraction, 1 ligand (GDP). MolNFT v1 #165133 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6TKZ
- Type
- protein
- Length
- 1,188 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q96BY6, P60953
- Ligands
- GDP
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | — | protein | 416 | — | Q96BY6 |
| C | — | protein | 177 | — | P60953 |
| D | — | protein | 178 | — | P60953 |
| A | — | protein | 417 | — | Q96BY6 |
Ligands and binding sites
- GDP · Guanosine-5'-diphosphate · ligand · 2 copies · chains C, D
- GOL · Glycerol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6TKZ · Crystal structure of the DHR2 domain of DOCK10 in complex with CDC42 · the same entry in another collection · chain B against B, TM-score 1.00
- Q96BY6 · AlphaFold monomer V2.0 prediction for dedicator of cytokinesis protein 10 (Q96BY6) · a predicted model of the same protein · chain B against A, TM-score 0.97
- P60953 · AlphaFold monomer V2.0 prediction for cell division control protein 42 homolog (P60953) · a predicted model of the same protein · chain D against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96BY6
- Every structure of UniProt P60953
- Elsewhere: RCSB PDB 6TKZ · PDBe 6TKZ · UniProt Q96BY6 · UniProt P60953
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