MolNFT v1 · #164193 · protein

Structure of a phosphomimetic switch 2 variant of RAB8A in complex with the phospho-rab binding domain of RILPL2

6SQ2: “Structure of a phosphomimetic switch 2 variant of RAB8A in complex with the phospho-rab binding domain of…”. X-ray diffraction, 2 ligands (GTP, MG). MolNFT v1 #164193 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6SQ2
Type: protein
Length: 412 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P61006, Q969X0
Ligands: GTP, MG

Structure

x-ray diffraction · 4 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	176	—	P61006
B	—	protein	173	—	P61006
D	—	protein	31	—	Q969X0
E	—	protein	32	—	Q969X0

Ligands and binding sites

GTP · Guanosine-5'-triphosphate · ligand · 2 copies · chains A, B
MG · Magnesium ion · metal · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6SQ2 · Structure of a phosphomimetic switch 2 variant of Rab8a in complex with the phospho-Rab… · the same entry in another collection · chain E against E, TM-score 1.00
P61006 · AlphaFold monomer V2.0 prediction for RAS-related protein rab-8A (P61006) · a predicted model of the same protein · chain B against A, TM-score 0.98
Q969X0 · AlphaFold monomer V2.0 prediction for rilp-like protein 2 (Q969X0) · a predicted model of the same protein · chain D against A, TM-score 0.79

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P61006
Every structure of UniProt Q969X0
Elsewhere: RCSB PDB 6SQ2 · PDBe 6SQ2 · UniProt P61006 · UniProt Q969X0

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