MolNFT v1 · #163887 · protein
X-ray structure of human glutamate carboxypeptidase II (gcpii) - the E424M inactive mutant, in complex with a sulfamide inhibitor gluglu
6SGP: “X-ray structure of human glutamate carboxypeptidase II (gcpii) - the E424M inactive mutant, in complex with a…”. X-ray diffraction, 7 ligands (NAG, MAN, BMA). MolNFT v1 #163887 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 6SGP
- Type
- protein
- Length
- 693 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q04609
- Ligands
- NAG, MAN, BMA, ZN, CA, NA, CL
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 693 | — | Q04609 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 13 copies · chains A
- MAN · alpha-D-mannopyranose · sugar · 3 copies · chains A
- BMA · beta-D-mannopyranose · sugar · 2 copies · chains A
- ZN · Zinc ion · metal · 2 copies · chains A
- CA · Calcium ion · metal · chains A
- NA · Sodium ion · metal · chains A
- CL · Chloride ion · ion · chains A
- PEG · Di(hydroxyethyl)ether · additive · 2 copies · chains A
- PGE · Triethylene glycol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6SGP · X-ray structure of human glutamate carboxypeptidase II (GCPII) - the E424M inactive… · the same entry in another collection · chain A against A, TM-score 1.00
- Q04609 · AlphaFold monomer V2.0 prediction for glutamate carboxypeptidase 2 (Q04609) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q04609
- Elsewhere: RCSB PDB 6SGP · PDBe 6SGP · UniProt Q04609
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