MolNFT v1 · #163652 · protein

EGFR-kinase in complex with compound 6

6S9D: “EGFR-kinase in complex with compound 6”. X-ray diffraction, 1 ligand (L3Z). MolNFT v1 #163652 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6S9D
Type: protein
Length: 300 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P00533
Ligands: L3Z

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	300	—	P00533

Ligands and binding sites

L3Z · 8-oxa-14,21,23,28-tetraazapentacyclo[23.3.1.02,7.014, 22.015,20]nonacosa-1(28),2(7),3,5,15,17,19,21,25(29), 26-decaen-24-one · ligand · chains A
DMS · Dimethyl sulfoxide · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6S9D · EGFR-kinase in complex with compound 6 · the same entry in another collection · chain A against A, TM-score 1.00
P00533 · AlphaFold monomer V2.0 prediction for epidermal growth factor receptor (P00533) · a predicted model of the same protein · chain A against A, TM-score 0.92

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P00533
Elsewhere: RCSB PDB 6S9D · PDBe 6S9D · UniProt P00533

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