Ligand · L3Z

L3Z · 8-oxa-14,21,23,28-tetraazapentacyclo[23.3.1.02,7.014, 22.015,20]nonacosa-1(28),2(7),3,5,15,17,19,21,25(29), 26-decaen-24-one

L3Z, 8-oxa-14,21,23,28-tetraazapentacyclo[23.3.1.02,7.014, 22.015,20]nonacosa-1(28),2(7),3,5,15,17,19,21,25(29), 26-decaen-24-one (C24 H22 N4 O2, 398.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component: L3Z
Formula: C24 H22 N4 O2
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

L3Z in 2 structures; the first of them:

6S9D · EGFR-kinase in complex with compound 6 · L3Z A1101 · binds LEU718, PHE723, VAL726, ALA743, LYS745, GLU762, CYS775, MET790 and 10 more
6S9D · EGFR-kinase in complex with compound 6 · L3Z A1101 · binds LEU718, PHE723, VAL726, ALA743, LYS745, GLU762, MET790, GLN791 and 8 more

Residues it binds most

LEU 2, MET 2, PHE 2, ALA 2, ARG 2, ASP 2, GLN 2, GLU 2, GLY 2, LYS 2 (residue and the binding sites it lines).

Found with

DMS · Dimethyl sulfoxide

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