MolNFT v1 · #161950 · protein
Crystal structure of phosphofructokinase from trypanosoma brucei in complex with an allosteric inhibitor CTCB360
6QU3: “Crystal structure of phosphofructokinase from trypanosoma brucei in complex with an allosteric inhibitor…”. X-ray diffraction, 1 ligand (JJ5). MolNFT v1 #161950 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6QU3
- Type
- protein
- Length
- 1,818 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O15648
- Ligands
- JJ5
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 465 | — | O15648 |
| B | — | protein | 446 | — | O15648 |
| C | — | protein | 446 | — | O15648 |
| D | — | protein | 461 | — | O15648 |
Ligands and binding sites
- JJ5 · 1-[(3,4-dichlorophenyl)methyl]-7~{H}-pyrrolo[3,2-c]pyridin-4-one · ligand · 4 copies · chains A, B, C, D
- CIT · Citric acid · additive · 4 copies · chains A, B, C, D
- GOL · Glycerol · additive · 4 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6QU3 · Crystal Structure of Phosphofructokinase from Trypanosoma brucei in complex with an… · the same entry in another collection · chain B against B, TM-score 1.00
- O15648 · AlphaFold monomer V2.0 prediction for ATP-dependent 6-phosphofructokinase (O15648) · a predicted model of the same protein · chain B against A, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O15648
- Elsewhere: RCSB PDB 6QU3 · PDBe 6QU3 · UniProt O15648
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