MolNFT v1 · #161105 · protein

Structure of human galactokinase in complex with galactose and 2'- (BENZO[D]OXAZOL-2-ylamino)-7',8'-dihydro-1'H-SPIRO[CYCLOHEXANE-1,4'- quinazolin]-5'(6'H)-one

6Q3X: “Structure of human galactokinase in complex with galactose and 2'…”. X-ray diffraction, 2 ligands (HFK, GAL). MolNFT v1 #161105 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6Q3X
Type: protein
Length: 780 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P51570
Ligands: HFK, GAL

Structure

x-ray diffraction · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	393	—	P51570
B	—	protein	387	—	P51570

Ligands and binding sites

HFK · 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one · ligand · 2 copies · chains A, B
GAL · beta-D-galactopyranose · sugar · 2 copies · chains A, B
MPD · (4S)-2-methyl-2,4-pentanediol · additive · 5 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6Q3X · Structure of human galactokinase in complex with galactose and… · the same entry in another collection · chain A against A, TM-score 1.00
P51570 · AlphaFold monomer V2.0 prediction for galactokinase (P51570) · a predicted model of the same protein · chain B against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P51570
Elsewhere: RCSB PDB 6Q3X · PDBe 6Q3X · UniProt P51570

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.