MolNFT v1 · #156147 · protein
Human PUF60 uhm domain (thioredoxin fusion) in complex with a small molecule binder
6LUR: “Human PUF60 uhm domain (thioredoxin fusion) in complex with a small molecule binder”. X-ray diffraction, 1 ligand (EVU). MolNFT v1 #156147 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6LUR
- Type
- protein
- Length
- 1,690 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P0AA25, Q9UHX1
- Ligands
- EVU
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, E, F, G, H | — | protein | 211 | — | P0AA25, Q9UHX1 |
| D | — | protein | 213 | — | P0AA25, Q9UHX1 |
Ligands and binding sites
- EVU · 4-[2-[4-(aminomethyl)phenyl]phenyl]piperazin-2-one · ligand · 8 copies · chains B, C, F, A, D, E
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6LUR · Human PUF60 UHM domain (thioredoxin fusion) in complex with a small molecule binder · the same entry in another collection · chain H against H, TM-score 1.00
- Q9UHX1 · AlphaFold monomer V2.0 prediction for POLY(U)-binding-splicing factor PUF60 (Q9UHX1) · a predicted model of the same protein · chain A against A, TM-score 0.52
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0AA25
- Every structure of UniProt Q9UHX1
- Elsewhere: RCSB PDB 6LUR · PDBe 6LUR · UniProt P0AA25 · UniProt Q9UHX1
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