MolNFT v1 · #156146 · protein
Haloperidol bound D2 dopamine receptor structure inspired discovery of subtype selective ligands
6LUQ: “Haloperidol bound D2 dopamine receptor structure inspired discovery of subtype selective ligands”. X-ray diffraction, 2 ligands (OLA, GMJ). MolNFT v1 #156146 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6LUQ
- Type
- protein
- Length
- 421 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P14416, D9IEF7
- Ligands
- OLA, GMJ
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 421 | — | P14416, D9IEF7 |
Ligands and binding sites
- OLA · Oleic acid · ligand · 4 copies · chains A
- GMJ · 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6LUQ · Haloperidol bound D2 dopamine receptor structure inspired discovery of subtype selective… · the same entry in another collection · chain A against A, TM-score 1.00
- P14416 · AlphaFold monomer V2.0 prediction for D(2) dopamine receptor (P14416) · a predicted model of the same protein · chain A against A, TM-score 0.64
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P14416
- Every structure of UniProt D9IEF7
- Elsewhere: RCSB PDB 6LUQ · PDBe 6LUQ · UniProt P14416 · UniProt D9IEF7
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.