MolNFT v1 · #155561 · protein

Structure of OR51B2 bound FEM1C

6LBG · Protein fem-1 homolog C,PEPTIDE from olfactory receptor 51B2: “Structure of OR51B2 bound FEM1C”. X-ray diffraction, 1 ligand (SO4), 5 pockets (best druggability 0.70). MolNFT v1 #155561 on GenesisL1: 3D structure, binding sites and…

PDB: 6LBG
Type: protein
Length: 759 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein fem-1 homolog C,PEPTIDE from olfactory receptor 51B2
UniProt: Q96JP0, Q9Y5P1
Ligands: SO4
Pockets: 5 · best druggability 0.70

Structure

x-ray diffraction · 2 distinct chains · 58% helix, 3% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
B	Protein fem-1 homolog C,PEPTIDE from olfactory receptor 51B2	protein	382	57% helix, 3% strand	Q96JP0, Q9Y5P1
A	Protein fem-1 homolog C,PEPTIDE from olfactory receptor 51B2	protein	377	59% helix, 3% strand	Q96JP0, Q9Y5P1

Ligands and binding sites

SO4 · Sulfate ion · ion · 6 copies · chains B, A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	758	0.70	0.77	66	SO4
2	106	0.54	0.83	23	empty
3	135	0.44	0.76	22	empty
4	79	0.35	0.76	16	empty
5	51	0.28	0.75	13	empty

Interfaces

1 interface between chains.

B–A · 1226 Å² buried · 10 hydrogen bonds · protein-protein

Compared structures

6LBG · Structure of OR51B2 bound FEM1C · the same entry in another collection · chain B against B, TM-score 1.00
Q96JP0 · AlphaFold monomer V2.0 prediction for protein fem-1 homolog C (Q96JP0) · a predicted model of the same protein · chain A against A, TM-score 0.96
Q9Y5P1 · AlphaFold monomer V2.0 prediction for olfactory receptor 51B2 (Q9Y5P1) · a predicted model of the same protein · chain A against A, TM-score 0.20

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q96JP0
Every structure of UniProt Q9Y5P1
Elsewhere: RCSB PDB 6LBG · PDBe 6LBG · UniProt Q96JP0 · UniProt Q9Y5P1

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.