UniProt Q96JP0
Protein fem-1 homolog C (Q96JP0)
Protein fem-1 homolog C (UniProt Q96JP0): 20 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 71 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q96JP0
- Protein
- Protein fem-1 homolog C
- Experimental structures
- 20
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 71 · 8 records with a druggable one
Structures
21 records of Q96JP0 in the MolNFT archive: 20 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6LBG | Structure of OR51B2 bound FEM1C | x-ray diffraction | B, A | SO4 | 5 (best 0.70) |
| 6LBG | Structure of OR51B2 bound FEM1C | x-ray diffraction | B, A | SO4 | — |
| 6LBN | Structure of SIL1-bound FEM1C | x-ray diffraction | A, B | — | — |
| 6LBN | Structure of SIL1-bound FEM1C | x-ray diffraction | A, B | — | — |
| 6LDP | Structure of CDK5R1-bound FEM1C | x-ray diffraction | A, B | SO4 | — |
| 6LDP | Structure of CDK5R1-bound FEM1C | x-ray diffraction | A, B | SO4 | — |
| 6LE6 | Structure of LNLPTQGRAR bound FEM1C | x-ray diffraction | A, B | SO4 | 7 (best 0.70) |
| 6LE6 | Structure of lnlptqgrar bound FEM1C | x-ray diffraction | A, B | SO4 | — |
| 6LEN | Structure of NS11 bound FEM1C | x-ray diffraction | A, B | — | 8 (best 0.55) |
| 6LEN | Structure of NS11 bound FEM1C | x-ray diffraction | A, B | — | — |
| 6LEY | Structure of Sil1G bound FEM1C | x-ray diffraction | A, B | — | — |
| 6LEY | Structure of SIL1G bound FEM1C | x-ray diffraction | A, B | — | — |
| 6LF0 | Structure of FEM1C | x-ray diffraction | A, B | SO4 | 8 (best 0.72) |
| 6LF0 | Structure of FEM1C | x-ray diffraction | A, B | SO4 | — |
| 6XKC | Crystal structure of E3 ligase | x-ray diffraction | A, B, C, D, E, F | — | 18 (best 0.80) |
| 6XKC | Crystal structure of E3 ligase | x-ray diffraction | A, B, C, D, E, F | — | — |
| 7JYA | Crystal structure of E3 ligase in complex with peptide | x-ray diffraction | A, B, C | UNX | 11 (best 0.78) |
| 7JYA | Crystal structure of E3 ligase in complex with peptide | x-ray diffraction | A, B, C | UNX | — |
| 8PQL | K48-linked ubiquitin chain formation with a cullin-RING E3 ligase and Cdc34… | electron microscopy | H | — | 8 (best 0.68) |
| 8Q7R | Ubiquitin ligation to substrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C… | electron microscopy | H | — | 6 (best 0.71) |
| Q96JP0 | AlphaFold monomer V2.0 prediction for protein fem-1 homolog C (Q96JP0) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7JYA chain B against the predicted model Q96JP0: TM-score 0.99, RMSD 0.89 Å
- 7JYA chain B against the predicted model Q96JP0: TM-score 0.99, RMSD 0.89 Å
- 7JYA chain A against the predicted model Q96JP0: TM-score 0.98, RMSD 1.02 Å
- 7JYA chain A against the predicted model Q96JP0: TM-score 0.98, RMSD 1.02 Å
- 7JYA chain C against the predicted model Q96JP0: TM-score 0.98, RMSD 1.05 Å
- 7JYA chain C against the predicted model Q96JP0: TM-score 0.98, RMSD 1.05 Å
- 6LEN chain B against the predicted model Q96JP0: TM-score 0.97, RMSD 0.98 Å
- 6LEN chain B against the predicted model Q96JP0: TM-score 0.97, RMSD 0.98 Å
- 6LE6 chain B against the predicted model Q96JP0: TM-score 0.97, RMSD 0.98 Å
- 6LE6 chain B against the predicted model Q96JP0: TM-score 0.97, RMSD 0.98 Å
Elsewhere
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