MolNFT v1 · #155448 · protein

Crystal structure of CET1 from trypanosoma cruzi in complex with tripolyphosphate, manganese and iodide ions.

6L7V · MRNA_TRIPASE domain-containing protein: “Crystal structure of CET1 from trypanosoma cruzi in complex with tripolyphosphate, manganese and iodide ions.”. X-ray diffraction, 3 ligands (3PO, MN, IOD), 1 pocket (best druggability 0.48).…

PDB: 6L7V
Type: protein
Length: 180 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: MRNA_TRIPASE domain-containing protein
UniProt: Q4E2I1
Ligands: 3PO, MN, IOD
Pockets: 1 · best druggability 0.48

Structure

x-ray diffraction · 1 distinct chain · 26% helix, 47% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	MRNA_TRIPASE domain-containing protein	protein	180	26% helix, 47% strand	Q4E2I1

Ligands and binding sites

3PO · Triphosphate · ligand · chains A
MN · Manganese (II) ion · metal · chains A
IOD · Iodide ion · ion · 7 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	246	0.48	0.74	29	MN, 3PO, IOD

Compared structures

6L7V · Crystal structure of Cet1 from Trypanosoma cruzi in complex with tripolyphosphate… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q4E2I1
Elsewhere: RCSB PDB 6L7V · PDBe 6L7V · UniProt Q4E2I1

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