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Crystal structure of CET1 from trypanosoma cruzi in complex with tripolyphosphate, manganese and iodide ions.

Analyse Crystal structure of CET1 from trypanosoma cruzi in complex with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6L7V
Type: protein
Length: 180 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: MRNA_TRIPASE domain-containing protein
UniProt: Q4E2I1
Ligands: 3PO, MN, IOD
Pockets: 1 · best druggability 0.48

Structure

x-ray diffraction · 1 distinct chain · 26% helix, 47% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	MRNA_TRIPASE domain-containing protein	protein	180	26% helix, 47% strand	Q4E2I1

Ligands and binding sites

3PO · Triphosphate · ligand · chains A
MN · Manganese (II) ion · metal · chains A
IOD · Iodide ion · ion · 7 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	246	0.48	0.74	29	MN, 3PO, IOD

Compared structures

6L7V · Crystal structure of Cet1 from Trypanosoma cruzi in complex with tripolyphosphate… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q4E2I1
Elsewhere: RCSB PDB 6L7V · PDBe 6L7V · UniProt Q4E2I1

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