MolNFT v1 · #155308 · protein
X-ray structure of human pparalpha ligand binding domain-GW9662- ciprofibrate co-crystals obtained by delipidation and co- crystallization
6L37: “X-ray structure of human pparalpha ligand binding domain-GW9662- ciprofibrate co-crystals obtained by…”. X-ray diffraction, 2 ligands (GW9, C5F). MolNFT v1 #155308 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6L37
- Type
- protein
- Length
- 539 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q07869
- Ligands
- GW9, C5F
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 270 | — | Q07869 |
| B | — | protein | 269 | — | Q07869 |
Ligands and binding sites
- GW9 · 2-chloro-5-nitro-N-phenylbenzamide · ligand · 6 copies · chains A, B
- C5F · 2-{4-[(1S)-2,2-dichlorocyclopropyl]phenoxy}-2-methylpropanoic acid · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6L37 · X-ray structure of human PPARalpha ligand binding domain-GW9662-ciprofibrate co-crystals… · the same entry in another collection · chain A against A, TM-score 1.00
- Q07869 · AlphaFold monomer V2.0 prediction for peroxisome proliferator- activated receptor alpha… · a predicted model of the same protein · chain B against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q07869
- Elsewhere: RCSB PDB 6L37 · PDBe 6L37 · UniProt Q07869
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