MolNFT v1 · #306340 · protein
AlphaFold monomer V2.0 prediction for peroxisome proliferator- activated receptor alpha (Q07869)
Q07869 · Peroxisome proliferator-activated receptor alpha: “AlphaFold monomer V2.0 prediction for peroxisome proliferator- activated receptor alpha (Q07869)”. 6 pockets (best druggability 0.84). MolNFT v1 #306340 on GenesisL1: 3D…
- Accession
- Q07869
- Type
- protein
- Length
- 468 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7a1388B6Aad67B04634A32f63b8A6D6005eab86c
- Molecule
- Peroxisome proliferator-activated receptor alpha
- UniProt
- Q07869
- Pockets
- 6 · best druggability 0.84
Structure
1 distinct chain · 52% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Peroxisome proliferator-activated receptor alpha | protein | 468 | 52% helix, 4% strand | Q07869 |
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 480 | 0.84 | 0.91 | 57 | empty |
| 2 | 106 | 0.43 | 0.78 | 25 | empty |
| 3 | 175 | 0.43 | 0.74 | 23 | empty |
| 4 | 156 | 0.37 | 0.72 | 20 | empty |
| 5 | 60 | 0.31 | 0.75 | 11 | empty |
Compared structures
- 3KDU · Crystal structure of peroxisome proliferator-activatedeceptor alpha (pparalpha) complex… · an experimental structure of the same protein · chain A against B, TM-score 0.57
- 3KDU · Crystal structure of peroxisome proliferator-activatedeceptor alpha (PPARalpha) complex… · an experimental structure of the same protein · chain A against B, TM-score 0.57
- 3KDT · Crystal structure of peroxisome proliferator-activatedeceptor alpha (PPARalpha) complex… · an experimental structure of the same protein · chain A against B, TM-score 0.57
- 3KDT · Crystal structure of peroxisome proliferator-activatedeceptor alpha (pparalpha) complex… · an experimental structure of the same protein · chain A against B, TM-score 0.57
- 3SP6 · Structural basis for iloprost as a dual PPARALPHA/DELTA agonist · an experimental structure of the same protein · chain A against A, TM-score 0.57
- 3SP6 · Structural basis for iloprost as a dual PPARalpha/delta agonist · an experimental structure of the same protein · chain A against A, TM-score 0.57
- 7BQ0 · X-ray structure of human pparalpha ligand binding domain-fenofibric acid-SRC1 coactivator… · an experimental structure of the same protein · chain A against A, TM-score 0.57
- 7BPY · X-ray structure of human pparalpha ligand binding domain-clofibric acid-SRC1 coactivator… · an experimental structure of the same protein · chain A against A, TM-score 0.57
- 6LX5 · X-ray structure of human pparalpha ligand binding domain-ciprofibrate co-crystals… · an experimental structure of the same protein · chain A against A, TM-score 0.57
- 6L38 · X-ray structure of human pparalpha ligand binding domain-GW9662- gemfibrozil co-crystals… · an experimental structure of the same protein · chain A against A, TM-score 0.57
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q07869
- Elsewhere: UniProt Q07869 · AlphaFold DB Q07869
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.