MolNFT v1 · #155179 · protein
Crystal structure of trkc in complex with 3-((6-(4-aminophenyl) IMIDAZO[1,2-A]PYRAZIN-3-YL)ETHYNYL)- N-(3-isopropyl-5-((4- methylpiperazin-1-YL)METHYL)PHENYL)-2- methylbenzamide
6KZD: “Crystal structure of trkc in complex with 3-((6-(4-aminophenyl) IMIDAZO[1,2-A]PYRAZIN-3-YL)ETHYNYL)…”. X-ray diffraction, 2 ligands (DZ6, PO4). MolNFT v1 #155179 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6KZD
- Type
- protein
- Length
- 282 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q16288
- Ligands
- DZ6, PO4
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 282 | — | Q16288 |
Ligands and binding sites
- DZ6 · 3-[2-[6-(4-aminophenyl)imidazo[1,2-a]pyrazin-3-yl]ethynyl]-2-methyl-~{N}-[3-(4-methylpiperazin-1-yl)-5-propan-2-yl-phenyl]benzamide · ligand · chains A
- PO4 · Phosphate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6KZD · Crystal structure of TRKc in complex with 3-((6-(4-aminophenyl)imidazo[1,2-a]pyrazin-3-yl)… · the same entry in another collection · chain A against A, TM-score 1.00
- Q16288 · AlphaFold monomer V2.0 prediction for nt-3 growth factor receptor (Q16288) · a predicted model of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q16288
- Elsewhere: RCSB PDB 6KZD · PDBe 6KZD · UniProt Q16288
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.