MolNFT v1 · #154389 · protein

Human lxr-beta in complex with an agonist

6K9M: “Human lxr-beta in complex with an agonist”. X-ray diffraction, 1 ligand (D43). MolNFT v1 #154389 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6K9M
Type: protein
Length: 965 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P55055
Ligands: D43

Structure

x-ray diffraction · 4 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	242	—	P55055
B	—	protein	241	—	P55055
C	—	protein	237	—	P55055
D	—	protein	245	—	P55055

Ligands and binding sites

D43 · ~{tert}-butyl (2'~{S},3~{S})-2-oxidanylidene-2'-propan-2-yl-spiro[1~{H}-indole-3,3'-pyrrolidine]-1'-carboxylate · ligand · 4 copies · chains A, B, C, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6K9M · Human LXR-beta in complex with an agonist · the same entry in another collection · chain D against D, TM-score 1.00
P55055 · AlphaFold monomer V2.0 prediction for oxysterols receptor lxr-beta (P55055) · a predicted model of the same protein · chain D against A, TM-score 0.92

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P55055
Elsewhere: RCSB PDB 6K9M · PDBe 6K9M · UniProt P55055

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