MolNFT v1 · #153994 · protein
Crystal structure of plasmodium falciparum hppk-dhps wild type with sdx-dhp
6JWX: “Crystal structure of plasmodium falciparum hppk-dhps wild type with sdx-dhp”. X-ray diffraction, 5 ligands (CKL, AMP, PH2). MolNFT v1 #153994 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6JWX
- Type
- protein
- Length
- 1,070 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q25704
- Ligands
- CKL, AMP, PH2, MG, CA
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 544 | — | Q25704 |
| B | — | protein | 526 | — | Q25704 |
Ligands and binding sites
- CKL · 4-[(2-azanyl-4-oxidanylidene-7,8-dihydro-3~{H}-pteridin-6-yl)methylamino]-~{N}-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide · ligand · 2 copies · chains A, B
- AMP · Adenosine monophosphate · ligand · 2 copies · chains A, B
- PH2 · 2-amino-6-hydroxymethyl-7,8-dihydro-3H-pteridin-4-one · ligand · chains A
- MG · Magnesium ion · metal · 2 copies · chains A, B
- CA · Calcium ion · metal · 2 copies · chains A, B
- ACT · Acetate ion · additive · 5 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6JWX · Crystal structure of Plasmodium falciparum HPPK-DHPS wild type with SDX-DHP · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q25704
- Elsewhere: RCSB PDB 6JWX · PDBe 6JWX · UniProt Q25704
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