MolNFT v1 · #153584 · protein

Crystal structure of OSHXK6-apo form

6JJ4 · Hexokinase-6: “Crystal structure of OSHXK6-apo form”. X-ray diffraction, 3 pockets (best druggability 0.65). MolNFT v1 #153584 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6JJ4
Type: protein
Length: 455 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Hexokinase-6
EC: 2.7.1.1
UniProt: Q8LQ68
Pockets: 3 · best druggability 0.65

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Hexokinase-6 (EC 2.7.1.1)	protein	455	40% helix, 19% strand	Q8LQ68

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	558	0.65	0.76	59	empty
2	114	0.48	0.80	22	empty
3	90	0.39	0.77	17	empty

Compared structures

6JJ4 · Crystal structure of OsHXK6-apo form · the same entry in another collection · chain A against A, TM-score 1.00
Q8LQ68 · AlphaFold monomer V2.0 prediction for hexokinase-6 (Q8LQ68) · a predicted model of the same protein · chain A against A, TM-score 0.92

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8LQ68
Elsewhere: RCSB PDB 6JJ4 · PDBe 6JJ4 · UniProt Q8LQ68

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