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Crystal structure of OSHXK6-apo form

Analyse Crystal structure of OSHXK6-apo form in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
6JJ4
Type
protein
Length
455 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Hexokinase-6
EC
2.7.1.1
UniProt
Q8LQ68
Pockets
3 · best druggability 0.65

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 19% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AHexokinase-6 (EC 2.7.1.1)protein45540% helix, 19% strandQ8LQ68

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
15580.650.7659empty
21140.480.8022empty
3900.390.7717empty

Compared structures

  • 6JJ4 · Crystal structure of OsHXK6-apo form · the same entry in another collection · chain A against A, TM-score 1.00
  • Q8LQ68 · AlphaFold monomer V2.0 prediction for hexokinase-6 (Q8LQ68) · a predicted model of the same protein · chain A against A, TM-score 0.92

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