UniProt Q8LQ68
Hexokinase-6 (Q8LQ68)
Hexokinase-6 (UniProt Q8LQ68), EC 2.7.1.1: 10 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 69 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8LQ68
- Protein
- Hexokinase-6
- EC
- 2.7.1.1
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 69 · 5 records with a druggable one
Structures
11 records of Q8LQ68 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5ZQT | Crystal structure of Oryza sativa hexokinase 6 | x-ray diffraction | A, B, C | ANP, MG, BGC | 20 (best 0.73) |
| 5ZQT | Crystal structure of oryza sativa hexokinase 6 | x-ray diffraction | A, B, C | ANP, MG, BGC | — |
| 6JJ4 | Crystal structure of OsHXK6-apo form | x-ray diffraction | A | — | 3 (best 0.65) |
| 6JJ4 | Crystal structure of OSHXK6-apo form | x-ray diffraction | A | — | — |
| 6JJ7 | Crystal structure of OsHXK6-Glc complex | x-ray diffraction | A, C, E | BGC | 15 (best 0.71) |
| 6JJ7 | Crystal structure of OSHXK6-glc complex | x-ray diffraction | A, C, E | BGC | — |
| 6JJ8 | Crystal structure of OsHXK6-ATP-Mg2+ complex | x-ray diffraction | C, A, B | ADP, PO4, MG | 17 (best 0.77) |
| 6JJ8 | Crystal structure of OSHXK6-ATP-MG2+ complex | x-ray diffraction | C, A, B | ADP, PO4, MG | — |
| 6JJ9 | Crystal structure of OsHXK6-Glc-ATP-Mg2+ complex | x-ray diffraction | C, A, E | ADP, PO4, MG, BGC | 14 (best 0.72) |
| 6JJ9 | Crystal structure of OSHXK6-glc-ATP-MG2+ complex | x-ray diffraction | C, A, E | ADP, PO4, MG, BGC | — |
| Q8LQ68 | AlphaFold monomer V2.0 prediction for hexokinase-6 (Q8LQ68) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5ZQT chain B against the predicted model Q8LQ68: TM-score 0.99, RMSD 0.63 Å
- 5ZQT chain C against the predicted model Q8LQ68: TM-score 0.99, RMSD 0.64 Å
- 5ZQT chain A against the predicted model Q8LQ68: TM-score 0.99, RMSD 0.70 Å
- 5ZQT chain A against the predicted model Q8LQ68: TM-score 0.99, RMSD 0.70 Å
- 6JJ7 chain C against the predicted model Q8LQ68: TM-score 0.99, RMSD 0.80 Å
- 6JJ8 chain B against the predicted model Q8LQ68: TM-score 0.99, RMSD 0.83 Å
- 6JJ8 chain A against the predicted model Q8LQ68: TM-score 0.99, RMSD 0.84 Å
- 6JJ7 chain E against the predicted model Q8LQ68: TM-score 0.99, RMSD 0.85 Å
- 6JJ9 chain E against the predicted model Q8LQ68: TM-score 0.99, RMSD 0.84 Å
- 6JJ7 chain A against the predicted model Q8LQ68: TM-score 0.99, RMSD 0.86 Å
Elsewhere
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