MolNFT v1 · #152099 · protein
Plasmodium falciparum myosin a, pre-powerstroke
6I7E · Myosin-a: “Plasmodium falciparum myosin a, pre-powerstroke”. X-ray diffraction, 3 ligands (ADP, MG, VO4), 8 pockets (best druggability 0.72). MolNFT v1 #152099 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6I7E
- Type
- protein
- Length
- 761 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Myosin-a
- UniProt
- Q8IDR3
- Ligands
- ADP, MG, VO4
- Pockets
- 8 · best druggability 0.72
Structure
x-ray diffraction · 1 distinct chain · 42% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Myosin-a | protein | 761 | 42% helix, 16% strand | Q8IDR3 |
Ligands and binding sites
- ADP · Adenosine-5'-diphosphate · ligand · chains A
- MG · Magnesium ion · metal · chains A
- VO4 · Vanadate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 752 | 0.72 | 0.78 | 73 | empty |
| 2 | 226 | 0.70 | 0.86 | 39 | empty |
| 3 | 505 | 0.67 | 0.78 | 62 | ADP, VO4 |
| 4 | 221 | 0.47 | 0.74 | 24 | empty |
| 5 | 130 | 0.44 | 0.76 | 23 | empty |
Modifications
Observed in the structure: 1 modified (phosphorylation).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8IDR3
- Elsewhere: RCSB PDB 6I7E · PDBe 6I7E · UniProt Q8IDR3
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