Crystal structure of plasmodium falciparum actin I (F54Y mutant) in the mg-ADP state

Structure

x-ray diffraction · 2 distinct chains.

Ligands and binding sites

• ADP · Adenosine-5'-diphosphate · ligand · chains A
• CA · Calcium ion · metal · 2 copies · chains G, A
• MG · Magnesium ion · metal
• K · Potassium ion · metal · chains A
• SCN · Thiocyanate ion · ion · 5 copies · chains A, G
• BTB · 2-[bis-(2-hydroxy-ethyl)-amino]-2-hydroxymethyl-propane-1,3-diol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 6I4J · Crystal Structure of Plasmodium falciparum actin I (F54Y mutant) in the Mg-ADP state · the same entry in another collection · chain A against A, TM-score 1.00
• Q8I4X0 · AlphaFold monomer V2.0 prediction for actin-1 (Q8I4X0) · a predicted model of the same protein · chain A against A, TM-score 0.98
• P13020 · AlphaFold monomer V2.0 prediction for gelsolin (P13020) · a predicted model of the same protein · chain G against A, TM-score 0.95

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q8I4X0
• Every structure of UniProt P13020
• Elsewhere: RCSB PDB 6I4J · PDBe 6I4J · UniProt Q8I4X0 · UniProt P13020