MolNFT v1 · #149574 · protein
Crystal structure of the periplasmic domain of tgpa from pseudomonas aeruginosa bound to ethylmercury
6G4H · Protein-glutamine gamma-glutamyltransferase: “Crystal structure of the periplasmic domain of tgpa from pseudomonas aeruginosa bound to ethylmercury”. X-ray diffraction, 2 ligands (EMC, PO4), 3 pockets (best druggability 0.57).…
- PDB
- 6G4H
- Type
- protein
- Length
- 278 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein-glutamine gamma-glutamyltransferase
- EC
- 2.3.2.13
- UniProt
- Q9HZX3
- Ligands
- EMC, PO4
- Pockets
- 3 · best druggability 0.57
Structure
x-ray diffraction · 1 distinct chain · 28% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein-glutamine gamma-glutamyltransferase (EC 2.3.2.13) | protein | 278 | 28% helix, 31% strand | Q9HZX3 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 118 | 0.57 | 0.84 | 23 | empty |
| 2 | 216 | 0.53 | 0.77 | 26 | empty |
| 3 | 117 | 0.50 | 0.81 | 18 | PO4, EMC |
Compared structures
- 6G4H · Crystal structure of the periplasmic domain of TgpA from Pseudomonas aeruginosa bound to… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9HZX3 · AlphaFold monomer V2.0 prediction for protein-glutamine gamma- glutamyltransferase… · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HZX3
- Elsewhere: RCSB PDB 6G4H · PDBe 6G4H · UniProt Q9HZX3
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.