MolNFT v1 · #149557 · protein
Structure of the mouse 8-oxoguanine DNA glycosylase MOGG1 in complex with ligand TH9525
6G40: “Structure of the mouse 8-oxoguanine DNA glycosylase MOGG1 in complex with ligand TH9525”. X-ray diffraction, 2 ligands (ELK, NI). MolNFT v1 #149557 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6G40
- Type
- protein
- Length
- 947 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O08760
- Ligands
- ELK, NI
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | — | protein | 316 | — | O08760 |
| C | — | protein | 315 | — | O08760 |
Ligands and binding sites
- ELK · ~{N}-(3-methoxy-4-methyl-phenyl)-4-(4-methoxy-2-oxidanylidene-3~{H}-benzimidazol-1-yl)piperidine-1-carboxamide · ligand · 3 copies · chains A, C, B
- NI · Nickel (II) ion · metal · chains A, B, C
- ACT · Acetate ion · additive · 4 copies · chains A, B, C
- PEG · Di(hydroxyethyl)ether · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6G40 · Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH9525 · the same entry in another collection · chain A against A, TM-score 1.00
- O08760 · AlphaFold monomer V2.0 prediction for N-GLYCOSYLASE/DNA lyase (O08760) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O08760
- Elsewhere: RCSB PDB 6G40 · PDBe 6G40 · UniProt O08760
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