MolNFT v1 · #149302 · protein + DNA
The crystal structure of POL2CORE-M644G in complex with DNA and an incoming nucleotide
6FWK: “The crystal structure of POL2CORE-M644G in complex with DNA and an incoming nucleotide”. X-ray diffraction, 3 ligands (DTP, CA, FE). MolNFT v1 #149302 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6FWK
- Type
- protein + DNA
- Length
- 2,254 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P21951
- Ligands
- DTP, CA, FE
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 1103 | — | P21951 |
| P, C | — | dna | 11 | — | — |
| T, D | — | dna | 15 | — | — |
| B | — | protein | 1099 | — | P21951 |
Ligands and binding sites
- DTP · 2'-deoxyadenosine 5'-triphosphate · ligand · 2 copies · chains A, P, T, B, C, D
- CA · Calcium ion · metal · 5 copies · chains A, B
- FE · Fe (III) ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6FWK · The crystal structure of Pol2CORE-M644G in complex with DNA and an incoming nucleotide · the same entry in another collection · chain D against D, TM-score 1.00
- P21951 · AlphaFold monomer V2.0 prediction for DNA polymerase epsilon catalytic subunit a (P21951) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P21951
- Elsewhere: RCSB PDB 6FWK · PDBe 6FWK · UniProt P21951
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