MolNFT v1 · #149251 · protein + RNA
Cryo-EM structure of the human CPSF160-WDR33-CPSF30 complex bound to the pas aauaaa motif at 3.1 ångström resolution
6FUW: “Cryo-EM structure of the human CPSF160-WDR33-CPSF30 complex bound to the pas aauaaa motif at 3.1 ångström…”. Electron microscopy, 1 ligand (ZN). MolNFT v1 #149251 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6FUW
- Type
- protein + RNA
- Length
- 1,673 residues
- Chains
- 4
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q10570, Q9C0J8, O95639
- Ligands
- ZN
Structure
electron microscopy · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 1181 | — | Q10570 |
| B | — | protein | 370 | — | Q9C0J8 |
| C | — | protein | 114 | — | O95639 |
| D | — | rna | 8 | — | — |
Ligands and binding sites
- ZN · Zinc ion · metal · 3 copies · chains C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6FUW · Cryo-EM structure of the human CPSF160-WDR33-CPSF30 complex bound to the PAS AAUAAA motif… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9C0J8 · AlphaFold monomer V2.0 prediction for pre-mRNA 3' end processing protein WDR33 (Q9C0J8) · a predicted model of the same protein · chain B against A, TM-score 0.99
- Q10570 · AlphaFold monomer V2.0 prediction for cleavage and polyadenylation specificity factor… · a predicted model of the same protein · chain A against A, TM-score 0.99
- O95639 · AlphaFold monomer V2.0 prediction for cleavage and polyadenylation specificity factor… · a predicted model of the same protein · chain C against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q10570
- Every structure of UniProt Q9C0J8
- Every structure of UniProt O95639
- Elsewhere: RCSB PDB 6FUW · PDBe 6FUW · UniProt Q10570 · UniProt Q9C0J8 · UniProt O95639
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