UniProt O95639
Cleavage and polyadenylation specificity factor subunit 4 (O95639)
Cleavage and polyadenylation specificity factor subunit 4 (UniProt O95639): 13 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 18 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- O95639
- Protein
- Cleavage and polyadenylation specificity factor subunit 4
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 18 · 4 records with a druggable one
Structures
14 records of O95639 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2D9N | Solution structure of CCCH type zinc-finger domain 2 in Cleavage and polyadenylation specificity… | solution nmr | A | — | — |
| 2D9N | Solution structure of ccch type zinc-finger domain 2 in cleavage and polyadenylation specificity… | solution nmr | A | — | — |
| 2RHK | Crystal structure of influenza A NS1A protein in complex with F2F3 fragment of human cellular… | x-ray diffraction | C, D | — | — |
| 2RHK | Crystal structure of influenza a NS1A protein in complex with F2F3 fragment of human cellular… | x-ray diffraction | C, D | — | — |
| 6DNH | Cryo-EM structure of human cpsf-160-WDR33-cpsf-30-pas RNA complex at 3.4 a resolution | electron microscopy | C | ZN | — |
| 6FBS | Cryo-EM structure of the human CPSF160-WDR33-CPSF30 complex bound to the pas aauaaa motif at 3.1… | electron microscopy | C | ZN | — |
| 6FUW | Cryo-EM structure of the human CPSF160-WDR33-CPSF30 complex bound to the pas aauaaa motif at 3.1… | electron microscopy | C | ZN | — |
| 6URG | Cryo-EM structure of human CPSF160-WDR33-CPSF30-CPSF100 PIM complex | electron microscopy | C | ZN | 4 (best 0.85) |
| 6URG | Cryo-EM structure of human CPSF160-WDR33-CPSF30-CPSF100 pim complex | electron microscopy | C | ZN | — |
| 6URO | Cryo-EM structure of human CPSF160-WDR33-CPSF30-PAS RNA-CstF77 complex | electron microscopy | C | ZN | 4 (best 0.85) |
| 6URO | Cryo-EM structure of human CPSF160-WDR33-CPSF30-pas RNA-CSTF77 complex | electron microscopy | C | ZN | — |
| 8E3I | CRYO-EM STRUCTURE OF the human MPSF IN COMPLEX WITH THE AUUAAA poly(A) signal | electron microscopy | C | ZN | 5 (best 0.86) |
| 8R8R | Cryo-EM structure of the human mPSF with PAPOA C-terminus peptide (PAPOAc) | electron microscopy | C | ZN | 5 (best 0.84) |
| O95639 | AlphaFold monomer V2.0 prediction for cleavage and polyadenylation specificity factor subunit 4… | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 9 records
Experiment against prediction
- 6FBS chain C against the predicted model O95639: TM-score 0.97, RMSD 0.70 Å
- 6FUW chain C against the predicted model O95639: TM-score 0.97, RMSD 0.70 Å
- 8R8R chain C against the predicted model O95639: TM-score 0.95, RMSD 0.91 Å
- 6URO chain C against the predicted model O95639: TM-score 0.93, RMSD 1.20 Å
- 6URO chain C against the predicted model O95639: TM-score 0.93, RMSD 1.20 Å
- 8E3I chain C against the predicted model O95639: TM-score 0.93, RMSD 1.15 Å
- 6DNH chain C against the predicted model O95639: TM-score 0.93, RMSD 1.16 Å
- 6URG chain C against the predicted model O95639: TM-score 0.89, RMSD 1.15 Å
- 6URG chain C against the predicted model O95639: TM-score 0.89, RMSD 1.15 Å
- 2RHK chain D against the predicted model O95639: TM-score 0.86, RMSD 1.42 Å
Elsewhere
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