UniProt Q10570
Cleavage and polyadenylation specificity factor subunit 1 (Q10570)
Cleavage and polyadenylation specificity factor subunit 1 (UniProt Q10570): 15 experimental structures and 1 predicted model on GenesisL1, 109 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q10570
- Protein
- Cleavage and polyadenylation specificity factor subunit 1
- Experimental structures
- 15
- Predicted models
- 1
- Pockets
- 109 · 7 records with a druggable one
Structures
16 records of Q10570 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6BLY | Cryo-EM structure of human CPSF-160-WDR33 complex at 3.36A resolution | electron microscopy | A | — | 14 (best 0.86) |
| 6BLY | Cryo-EM structure of human cpsf-160-WDR33 complex at 3.36A resolution | electron microscopy | A | — | — |
| 6BM0 | Cryo-EM structure of human CPSF-160-WDR33 complex at 3.8 A resolution | electron microscopy | A | — | 15 (best 0.88) |
| 6BM0 | Cryo-EM structure of human cpsf-160-WDR33 complex at 3.8 a resolution | electron microscopy | A | — | — |
| 6DNH | Cryo-EM structure of human cpsf-160-WDR33-cpsf-30-pas RNA complex at 3.4 a resolution | electron microscopy | A | — | — |
| 6F9N | Crystal structure of the human CPSF160-WDR33 complex | x-ray diffraction | A | — | — |
| 6FBS | Cryo-EM structure of the human CPSF160-WDR33-CPSF30 complex bound to the pas aauaaa motif at 3.1… | electron microscopy | A | — | — |
| 6FUW | Cryo-EM structure of the human CPSF160-WDR33-CPSF30 complex bound to the PAS AAUAAA motif at 3.1… | electron microscopy | A | — | 18 (best 0.87) |
| 6FUW | Cryo-EM structure of the human CPSF160-WDR33-CPSF30 complex bound to the pas aauaaa motif at 3.1… | electron microscopy | A | — | — |
| 6URG | Cryo-EM structure of human CPSF160-WDR33-CPSF30-CPSF100 PIM complex | electron microscopy | A | — | 19 (best 0.88) |
| 6URG | Cryo-EM structure of human CPSF160-WDR33-CPSF30-CPSF100 pim complex | electron microscopy | A | — | — |
| 6URO | Cryo-EM structure of human CPSF160-WDR33-CPSF30-PAS RNA-CstF77 complex | electron microscopy | A | — | 13 (best 0.87) |
| 6URO | Cryo-EM structure of human CPSF160-WDR33-CPSF30-pas RNA-CSTF77 complex | electron microscopy | A | — | — |
| 8E3I | CRYO-EM STRUCTURE OF the human MPSF IN COMPLEX WITH THE AUUAAA poly(A) signal | electron microscopy | A | — | 12 (best 0.88) |
| 8R8R | Cryo-EM structure of the human mPSF with PAPOA C-terminus peptide (PAPOAc) | electron microscopy | A | — | 18 (best 0.87) |
| Q10570 | AlphaFold monomer V2.0 prediction for cleavage and polyadenylation specificity factor subunit 1… | predicted | A | — | — |
Experiment against prediction
- 6URG chain A against the predicted model Q10570: TM-score 0.99, RMSD 1.04 Å
- 6URG chain A against the predicted model Q10570: TM-score 0.99, RMSD 1.04 Å
- 6BLY chain A against the predicted model Q10570: TM-score 0.99, RMSD 1.08 Å
- 6BLY chain A against the predicted model Q10570: TM-score 0.99, RMSD 1.08 Å
- 8E3I chain A against the predicted model Q10570: TM-score 0.99, RMSD 1.08 Å
- 6F9N chain A against the predicted model Q10570: TM-score 0.99, RMSD 1.13 Å
- 6DNH chain A against the predicted model Q10570: TM-score 0.99, RMSD 1.10 Å
- 6BM0 chain A against the predicted model Q10570: TM-score 0.99, RMSD 1.11 Å
- 6BM0 chain A against the predicted model Q10570: TM-score 0.99, RMSD 1.11 Å
- 6URO chain A against the predicted model Q10570: TM-score 0.99, RMSD 1.16 Å
Elsewhere
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