MolNFT v1 · #149207 · protein

MPI3KD in complex with AZ2

6FTN: “MPI3KD in complex with AZ2”. X-ray diffraction, 1 ligand (E78). MolNFT v1 #149207 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6FTN
Type: protein
Length: 827 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: O35904
Ligands: E78

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	827	—	O35904

Ligands and binding sites

E78 · ~{N}-[5-[2-[(1~{S})-1-cyclopropylethyl]-7-methyl-1-oxidanylidene-3~{H}-isoindol-5-yl]-4-methyl-1,3-thiazol-2-yl]ethanamide · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6FTN · mPI3Kd IN COMPLEX WITH AZ2 · the same entry in another collection · chain A against A, TM-score 1.00
O35904 · AlphaFold monomer V2.0 prediction for phosphatidylinositol 4,5-bisphosphate 3-kinase… · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O35904
Elsewhere: RCSB PDB 6FTN · PDBe 6FTN · UniProt O35904

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