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MolNFT v1 · #148765 · protein

Crystal structure of gephyrin E domain in complex with artesunate

6FGC: “Crystal structure of gephyrin E domain in complex with artesunate”. X-ray diffraction, 5 ligands (ADP, D95, CA). MolNFT v1 #148765 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6FGC
Type
protein
Length
412 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
Q03555
Ligands
ADP, D95, CA, PO4, CL

Structure

x-ray diffraction · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein412—Q03555

Ligands and binding sites

  • ADP · Adenosine-5'-diphosphate · ligand · chains A
  • D95 · Artesunate · ligand · chains A
  • CA · Calcium ion · metal
  • PO4 · Phosphate ion · ion · chains A
  • CL · Chloride ion · ion · chains A
  • ACT · Acetate ion · additive · 10 copies · chains A
  • MPD · (4S)-2-methyl-2,4-pentanediol · additive · chains A
  • MRD · (4R)-2-methylpentane-2,4-diol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6FGC · Crystal structure of Gephyrin E domain in complex with Artesunate · the same entry in another collection · chain A against A, TM-score 1.00
  • Q03555 · AlphaFold monomer V2.0 prediction for gephyrin (Q03555) · a predicted model of the same protein · chain A against A, TM-score 0.98

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