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MolNFT v1 · #148149 · protein

Re-refinement of the MCM2-7 double hexamer using isolde

6EYC: “Re-refinement of the MCM2-7 double hexamer using isolde”. Electron microscopy, 2 ligands (ADP, ZN). MolNFT v1 #148149 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6EYC
Type
protein
Length
3,787 residues
Chains
6
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P29469, P24279, P30665, P29496, P53091, P38132
Ligands
ADP, ZN

Structure

electron microscopy · 6 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
2—protein603—P29469
3—protein605—P24279
4—protein641—P30665
5—protein633—P29496
6—protein616—P53091
7—protein689—P38132

Ligands and binding sites

  • ADP · Adenosine-5'-diphosphate · ligand · 6 copies · chains 2, 6, 3, 5, 7, 4
  • ZN · Zinc ion · metal · 5 copies · chains 2, 4, 5, 6, 7

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6EYC · Re-refinement of the MCM2-7 double hexamer using ISOLDE · the same entry in another collection · chain 7 against 7, TM-score 1.00
  • P38132 · AlphaFold monomer V2.0 prediction for DNA replication licensing factor MCM7 (P38132) · a predicted model of the same protein · chain 7 against A, TM-score 0.91
  • P24279 · AlphaFold monomer V2.0 prediction for DNA replication licensing factor MCM3 (P24279) · a predicted model of the same protein · chain 3 against A, TM-score 0.87
  • P29496 · AlphaFold monomer V2.0 prediction for minichromosome maintenance protein 5 (P29496) · a predicted model of the same protein · chain 5 against A, TM-score 0.67

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