MolNFT v1 · #147017 · protein
Wild type human serotonin transporter in complex with 15B8 Fab bound to ibogaine in occluded conformation
6DZV: “Wild type human serotonin transporter in complex with 15B8 Fab bound to ibogaine in occluded conformation”. Electron microscopy, 3 ligands (HJM, Y01, NAG). MolNFT v1 #147017 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 6DZV
- Type
- protein
- Length
- 765 residues
- Chains
- 3
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P31645
- Ligands
- HJM, Y01, NAG
Structure
electron microscopy · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 537 | — | P31645 |
| B | — | protein | 118 | — | — |
| C | — | protein | 110 | — | — |
Ligands and binding sites
- HJM · (5beta)-12-methoxyibogamine · ligand · chains A
- Y01 · Cholesterol hemisuccinate · ligand · chains A
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6DZV · Wild type human serotonin transporter in complex with 15B8 Fab bound to ibogaine in… · the same entry in another collection · chain A against A, TM-score 1.00
- P31645 · AlphaFold monomer V2.0 prediction for sodium-dependent serotonin transporter (P31645) · a predicted model of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P31645
- Elsewhere: RCSB PDB 6DZV · PDBe 6DZV · UniProt P31645
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