Research workbench
Wild type human serotonin transporter in complex with 15B8 Fab bound to ibogaine in occluded conformation
Analyse Wild type human serotonin transporter in complex with 15B8 Fab bound to… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6DZV
- Type
- protein
- Length
- 765 residues
- Chains
- 3
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P31645
- Ligands
- HJM, Y01, NAG
Structure
electron microscopy · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 537 | — | P31645 |
| B | — | protein | 118 | — | — |
| C | — | protein | 110 | — | — |
Ligands and binding sites
- HJM · (5beta)-12-methoxyibogamine · ligand · chains A
- Y01 · Cholesterol hemisuccinate · ligand · chains A
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6DZV · Wild type human serotonin transporter in complex with 15B8 Fab bound to ibogaine in… · the same entry in another collection · chain A against A, TM-score 1.00
- P31645 · AlphaFold monomer V2.0 prediction for sodium-dependent serotonin transporter (P31645) · a predicted model of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P31645
- Elsewhere: RCSB PDB 6DZV · PDBe 6DZV · UniProt P31645
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