MolNFT v1 · #145782 · protein
Crystal structure of signal recognition particle receptor ftsy from elizabethkingia anophelis in complex with GDP
6CY5: “Crystal structure of signal recognition particle receptor ftsy from elizabethkingia anophelis in complex with…”. X-ray diffraction, 2 ligands (GDP, MG), 8 pockets (best druggability 0.72). MolNFT v1 #145782 on GenesisL1: 3D…
- PDB
- 6CY5
- Type
- protein
- Length
- 634 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Signal recognition particle receptor ftsy
- UniProt
- A0A077EFA5
- Ligands
- GDP, MG
- Pockets
- 8 · best druggability 0.72
Structure
x-ray diffraction · 2 distinct chains · 51% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Signal recognition particle receptor ftsy | protein | 316 | 51% helix, 14% strand | A0A077EFA5 |
| B | Signal recognition particle receptor ftsy | protein | 318 | 51% helix, 14% strand | A0A077EFA5 |
Ligands and binding sites
- GDP · Guanosine-5'-diphosphate · ligand · 3 copies · chains A, B
- MG · Magnesium ion · metal · 2 copies · chains A, B
- EDO · 1,2-ethanediol · additive · 8 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
8 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 831 | 0.72 | 0.78 | 77 | MG, EDO |
| 2 | 86 | 0.41 | 0.79 | 18 | empty |
| 3 | 96 | 0.40 | 0.77 | 19 | empty |
| 4 | 137 | 0.38 | 0.73 | 24 | empty |
| 5 | 78 | 0.33 | 0.74 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 534 Ų buried · 15 hydrogen bonds · protein-protein
Compared structures
- 6CY5 · Crystal structure of Signal recognition particle receptor FtsY from Elizabethkingia… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A077EFA5
- Elsewhere: RCSB PDB 6CY5 · PDBe 6CY5 · UniProt A0A077EFA5
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