MolNFT v1 · #144979 · protein

Crystal structure of ndm-1 metallo-beta-lactamase harboring an insertion of a pro residue in L3 loop

6CAC: “Crystal structure of ndm-1 metallo-beta-lactamase harboring an insertion of a pro residue in L3 loop”. X-ray diffraction, 6 ligands (NI, ZN, CD). MolNFT v1 #144979 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6CAC
Type: protein
Length: 928 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: C7C422
Ligands: NI, ZN, CD, CO, CA, SO4

Structure

x-ray diffraction · 3 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, C	—	protein	234	—	C7C422
B	—	protein	229	—	C7C422
D	—	protein	231	—	C7C422

Ligands and binding sites

NI · Nickel (II) ion · metal · 5 copies · chains A, D, B, C
ZN · Zinc ion · metal · 4 copies · chains A, B, C, D
CD · Cadmium ion · metal · 4 copies · chains A, B, C, D
CO · Cobalt (II) ion · metal · 4 copies · chains A, B, C, D
CA · Calcium ion · metal · 4 copies · chains A, B, C, D
SO4 · Sulfate ion · ion · 9 copies · chains A, B, C, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6CAC · Crystal structure of NDM-1 metallo-beta-lactamase harboring an insertion of a Pro residue… · the same entry in another collection · chain D against D, TM-score 1.00
C7C422 · AlphaFold monomer V2.0 prediction for metallo-beta-lactamase type 2 (C7C422) · a predicted model of the same protein · chain D against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt C7C422
Elsewhere: RCSB PDB 6CAC · PDBe 6CAC · UniProt C7C422

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