MolNFT v1 · #144703 · protein
Phosphoinositide 3-kinase gamma bound to an pyrrolopyridinone inhibitor
6C1S: “Phosphoinositide 3-kinase gamma bound to an pyrrolopyridinone inhibitor”. X-ray diffraction, 2 ligands (EFV, SO4). MolNFT v1 #144703 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6C1S
- Type
- protein
- Length
- 826 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P48736
- Ligands
- EFV, SO4
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 826 | — | P48736 |
Ligands and binding sites
- EFV · {4-[2-(5,6-dimethoxypyridin-3-yl)-5-oxo-5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-1H-pyrazol-1-yl}acetonitrile · ligand · chains A
- SO4 · Sulfate ion · ion · 4 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6C1S · Phosphoinositide 3-Kinase gamma bound to an pyrrolopyridi Inhibitor · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P48736
- Elsewhere: RCSB PDB 6C1S · PDBe 6C1S · UniProt P48736
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.