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Ligand · EFV

EFV · {4-[2-(5,6-dimethoxypyridin-3-yl)-5-oxo-5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-1H-pyrazol-1-yl}acetonitrile

EFV, {4-[2-(5,6-dimethoxypyridin-3-yl)-5-oxo-5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-1H-pyrazol-1-yl}acetonitrile (C19 H16 N6 O3, 376.4 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record (1 PDB entry). Every binding site…

Component
EFV
Formula
C19 H16 N6 O3
Class
ligand
Structures
1
PDB entries
1

Binding sites

EFV in 1 structure; the first of them:

  • 6C1S · Phosphoinositide 3-kinase gamma bound to an pyrrolopyridinone inhibitor · EFV A1201 · binds PRO810, TRP812, ILE831, LYS833, ASP836, LEU838, ASP841, TYR867 and 9 more

Residues it binds most

ILE 1, ASP 1, LYS 1, ALA 1, GLU 1, LEU 1, MET 1, PRO 1, TRP 1, TYR 1 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

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