MolNFT v1 · #143863 · protein
Cryo X-ray structure of sisomicin bound aac-via
6BC3 · Aac 3-VI protein: “Cryo X-ray structure of sisomicin bound aac-via”. X-ray diffraction, 2 ligands (COA, SIS), 1 pocket (best druggability 0.53). MolNFT v1 #143863 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6BC3
- Type
- protein
- Length
- 268 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Aac 3-VI protein
- UniProt
- Q47030
- Ligands
- COA, SIS
- Pockets
- 1 · best druggability 0.53
Structure
x-ray diffraction · 1 distinct chain · 36% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Aac 3-VI protein | protein | 268 | 36% helix, 22% strand | Q47030 |
Ligands and binding sites
- COA · Coenzyme A · ligand · chains A
- SIS · (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 230 | 0.53 | 0.77 | 36 | SIS |
Compared structures
- 6BC3 · Cryo X-ray structure of sisomicin bound AAC-VIa · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q47030
- Elsewhere: RCSB PDB 6BC3 · PDBe 6BC3 · UniProt Q47030
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.