MolNFT v1 · #143857 · protein

Structure of the major pilin protein (T3.2) from streptococcus pyogenes serotype GAS13637

6BBW · Major pilin backbone protein T-antigen, T3.2.: “Structure of the major pilin protein (T3.2) from streptococcus pyogenes serotype GAS13637”. X-ray diffraction, 1 ligand (CA), 2 pockets (best druggability 0.60). MolNFT v1 #143857 on…

PDB: 6BBW
Type: protein
Length: 560 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Major pilin backbone protein T-antigen, T3.2.
UniProt: A0A096ZHB0
Ligands: CA
Pockets: 2 · best druggability 0.60

Structure

x-ray diffraction · 1 distinct chain · 2% helix, 50% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Major pilin backbone protein T-antigen, T3.2.	protein	280	2% helix, 50% strand	A0A096ZHB0

Ligands and binding sites

CA · Calcium ion · metal · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	556	0.60	0.74	49	empty
2	303	0.55	0.76	30	empty

Interfaces

1 interface between chains.

A–B · 373 Å² buried · 3 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 isopeptide (isopeptide).

Compared structures

6BBW · Structure of the major pilin protein (T3.2) from Streptococcus pyogenes serotype GAS13637 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A096ZHB0
Elsewhere: RCSB PDB 6BBW · PDBe 6BBW · UniProt A0A096ZHB0

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