Research workbench
Structure of the major pilin protein (T3.2) from streptococcus pyogenes serotype GAS13637
Analyse Structure of the major pilin protein (T3.2) from streptococcus pyogenes… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6BBW
- Type
- protein
- Length
- 560 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Major pilin backbone protein T-antigen, T3.2.
- UniProt
- A0A096ZHB0
- Ligands
- CA
- Pockets
- 2 · best druggability 0.60
Structure
x-ray diffraction · 1 distinct chain · 2% helix, 50% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Major pilin backbone protein T-antigen, T3.2. | protein | 280 | 2% helix, 50% strand | A0A096ZHB0 |
Ligands and binding sites
- CA · Calcium ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 556 | 0.60 | 0.74 | 49 | empty |
| 2 | 303 | 0.55 | 0.76 | 30 | empty |
Interfaces
1 interface between chains.
- A–B · 373 Ų buried · 3 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 isopeptide (isopeptide).
Compared structures
- 6BBW · Structure of the major pilin protein (T3.2) from Streptococcus pyogenes serotype GAS13637 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A096ZHB0
- Elsewhere: RCSB PDB 6BBW · PDBe 6BBW · UniProt A0A096ZHB0
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