MolNFT v1 · #143602 · protein

Crystal structure of human GLE1 ctd-NUP42 gbm-DDX19B(ADP) complex

6B4I: “Crystal structure of human GLE1 ctd-NUP42 gbm-DDX19B(ADP) complex”. X-ray diffraction, 2 ligands (ADP, PO4). MolNFT v1 #143602 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6B4I
Type: protein
Length: 1,564 residues
Chains: 6
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q53GS7, Q3B7J4, Q9UMR2
Ligands: ADP, PO4

Structure

x-ray diffraction · 6 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
B	—	protein	315	—	Q53GS7
C	—	protein	45	—	Q3B7J4
A	—	protein	314	—	Q53GS7
D	—	protein	39	—	Q3B7J4
E	—	protein	425	—	Q9UMR2
F	—	protein	426	—	Q9UMR2

Ligands and binding sites

ADP · Adenosine-5'-diphosphate · ligand · 2 copies · chains E, F
PO4 · Phosphate ion · ion · 6 copies · chains B, A, E, F

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6B4I · Crystal structure of human Gle1 CTD-Nup42 GBM-DDX19B(ADP) complex · the same entry in another collection · chain F against F, TM-score 1.00
Q53GS7 · AlphaFold monomer V2.0 prediction for nucleoporin GLE1 (Q53GS7) · a predicted model of the same protein · chain A against A, TM-score 0.99
Q9UMR2 · AlphaFold monomer V2.0 prediction for ATP-dependent RNA helicase DDX19B (Q9UMR2) · a predicted model of the same protein · chain E against A, TM-score 0.90

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q53GS7
Every structure of UniProt Q3B7J4
Every structure of UniProt Q9UMR2
Elsewhere: RCSB PDB 6B4I · PDBe 6B4I · UniProt Q53GS7 · UniProt Q3B7J4 · UniProt Q9UMR2

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