UniProt Q53GS7
Nucleoporin GLE1 (Q53GS7)
Nucleoporin GLE1 (UniProt Q53GS7): 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 81 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q53GS7
- Protein
- Nucleoporin GLE1
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 81 · 6 records with a druggable one
Structures
7 records of Q53GS7 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6B4F | Crystal structure of human Gle1 CTD-Nup42 GBM complex | x-ray diffraction | B, A | PO4, CL | 11 (best 0.64) |
| 6B4F | Crystal structure of human GLE1 ctd-NUP42 gbm complex | x-ray diffraction | B, A | PO4, CL | 11 (best 0.64) |
| 6B4I | Crystal structure of human Gle1 CTD-Nup42 GBM-DDX19B(ADP) complex | x-ray diffraction | B, A | PO4 | 15 (best 0.83) |
| 6B4I | Crystal structure of human GLE1 ctd-NUP42 gbm-DDX19B(ADP) complex | x-ray diffraction | B, A | PO4 | 15 (best 0.83) |
| 6B4J | Crystal structure of human Gle1 CTD-Nup42 GBM-DDX19B(AMPPNP) complex | x-ray diffraction | B, A | PO4 | 14 (best 0.82) |
| 6B4J | Crystal structure of human GLE1 ctd-NUP42 gbm-DDX19B(AMPPNP) complex | x-ray diffraction | B, A | PO4 | 14 (best 0.82) |
| Q53GS7 | AlphaFold monomer V2.0 prediction for nucleoporin GLE1 (Q53GS7) | predicted | A | — | 1 (best 0.30) |
Ligands
Experiment against prediction
- 6B4J chain A against the predicted model Q53GS7: TM-score 0.99, RMSD 0.62 Å
- 6B4J chain A against the predicted model Q53GS7: TM-score 0.99, RMSD 0.62 Å
- 6B4J chain B against the predicted model Q53GS7: TM-score 0.99, RMSD 0.67 Å
- 6B4J chain B against the predicted model Q53GS7: TM-score 0.99, RMSD 0.67 Å
- 6B4I chain A against the predicted model Q53GS7: TM-score 0.99, RMSD 0.67 Å
- 6B4I chain A against the predicted model Q53GS7: TM-score 0.99, RMSD 0.67 Å
- 6B4I chain B against the predicted model Q53GS7: TM-score 0.99, RMSD 0.72 Å
- 6B4I chain B against the predicted model Q53GS7: TM-score 0.99, RMSD 0.72 Å
- 6B4F chain B against the predicted model Q53GS7: TM-score 0.99, RMSD 0.74 Å
- 6B4F chain B against the predicted model Q53GS7: TM-score 0.99, RMSD 0.74 Å
Elsewhere
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