MolNFT v1 · #143308 · protein
The therapeutic antibody LM609 selectively inhibits ligand binding to human alpha-V beta-3 integrin via steric hindrance
6AVQ: “The therapeutic antibody LM609 selectively inhibits ligand binding to human alpha-V beta-3 integrin via…”. Electron microscopy. MolNFT v1 #143308 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6AVQ
- Type
- protein
- Length
- 2,040 residues
- Chains
- 4
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P06756, P05106
Structure
electron microscopy · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 927 | — | P06756 |
| B | — | protein | 688 | — | P05106 |
| H | — | protein | 214 | — | — |
| L | — | protein | 211 | — | — |
Compared structures
- 6AVQ · The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human alpha-V… · the same entry in another collection · chain A against A, TM-score 1.00
- P06756 · AlphaFold monomer V2.0 prediction for integrin alpha-V (P06756) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P06756
- Every structure of UniProt P05106
- Elsewhere: RCSB PDB 6AVQ · PDBe 6AVQ · UniProt P06756 · UniProt P05106
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.